| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Macs Corner | city | South Dakota | United States | 44.25 | -99.44 | 1811 | |
| Madison | city | South Dakota | United States | 44.01 | -97.11 | 1669 | |
| Madra | city | South Dakota | United States | 45.93 | -99.72 | 1965 | |
| Madsen Beach | city | South Dakota | United States | 45.46 | -96.74 | 1013 | |
| Mahto | city | South Dakota | United States | 45.76 | -100.68 | 1797 | |
| Maitland | city | South Dakota | United States | 44.40 | -103.80 | 5078 | |
| Manchester | city | South Dakota | United States | 44.37 | -97.72 | 1669 | |
| Manderson | city | South Dakota | United States | 43.24 | -102.47 | 3349 | |
| Mansfield | city | South Dakota | United States | 45.24 | -98.56 | 1669 | |
| Maple Leaf | city | South Dakota | United States | 45.92 | -100.89 | 2509 | |
| Marcus | city | South Dakota | United States | 44.66 | -102.27 | 2572 | |
| Marietta | city | South Dakota | United States | 43.39 | -103.92 | 3599 | |
| Marion | city | South Dakota | United States | 43.42 | -97.26 | 1669 | |
| Marksville | city | South Dakota | United States | 45.07 | -100.38 | 1699 | |
| Marlow | city | South Dakota | United States | 45.92 | -97.39 | 1669 | |
| Marshalltown (historical) | city | South Dakota | United States | 42.94 | -96.90 | 1200 | |
| Martin | city | South Dakota | United States | 43.17 | -101.73 | 3349 | |
| Martindale Addition | city | South Dakota | United States | 43.59 | -96.77 | 1669 | |
| Marty | city | South Dakota | United States | 42.99 | -98.43 | 1669 | |
| Marvin | city | South Dakota | United States | 45.26 | -96.91 | 1669 | |
| Maurice | city | South Dakota | United States | 44.40 | -103.90 | 5029 | |
| Maurine | city | South Dakota | United States | 45.02 | -102.59 | 2896 | |
| Mawl Springs | city | South Dakota | United States | 44.09 | -102.80 | 2805 | |
| Maxwell Colony | city | South Dakota | United States | 43.18 | -97.63 | 1207 | |
| Mayfield | city | South Dakota | United States | 43.08 | -97.32 | 1669 | |
| Mayfield Colony | city | South Dakota | United States | 44.70 | -97.58 | 1765 | |
| Maywood (historical) | city | South Dakota | United States | 43.51 | -97.95 | 1669 | |
| McCook Lake | city | South Dakota | United States | 42.54 | -96.51 | 1099 | |
| McCroskey Addition | city | South Dakota | United States | 43.65 | -96.69 | 1669 | |
| McGee | city | South Dakota | United States | 44.04 | -103.38 | 4189 | |
| McIntosh | city | South Dakota | United States | 45.92 | -101.35 | 2509 | |
| McKays Trailer Court | city | South Dakota | United States | 42.61 | -96.64 | 1125 | |
| McLaughlin | city | South Dakota | United States | 45.81 | -100.81 | 2024 | |
| Meadow | city | South Dakota | United States | 45.53 | -102.22 | 2700 | |
| Meadow View Addition | city | South Dakota | United States | 43.62 | -96.71 | 1669 | |
| Meckling | city | South Dakota | United States | 42.84 | -97.07 | 1154 | |
| Medary | city | South Dakota | United States | 44.21 | -96.79 | 1669 | |
| Melcore Acres Subdivision | city | South Dakota | United States | 44.08 | -103.44 | 4399 | |
| Melham | city | South Dakota | United States | 44.56 | -97.69 | 1801 | |
| Mellette | city | South Dakota | United States | 45.15 | -98.50 | 1669 | |
| Melrose Addition | city | South Dakota | United States | 45.45 | -98.46 | 1669 | |
| Menno | city | South Dakota | United States | 43.24 | -97.58 | 1669 | |
| Merritt | city | South Dakota | United States | 44.14 | -103.57 | 5196 | |
| Merton (historical) | city | South Dakota | United States | 44.76 | -97.86 | 1669 | |
| Metzgerville | city | South Dakota | United States | 43.54 | -98.26 | 1669 | |
| Midland | city | South Dakota | United States | 44.07 | -101.16 | 1853 | |
| Midway | city | South Dakota | United States | 43.70 | -96.71 | 1669 | |
| Midway | city | South Dakota | United States | 43.13 | -97.40 | 1669 | |
| Midway | city | South Dakota | United States | 42.87 | -96.79 | 1669 | |
| Milbank | city | South Dakota | United States | 45.22 | -96.64 | 1135 | |
| Milbank Subdivision | city | South Dakota | United States | 45.22 | -96.61 | 1141 | |
| Milesville | city | South Dakota | United States | 44.46 | -101.68 | 2509 | |
| Millard | city | South Dakota | United States | 45.15 | -99.19 | 1669 | |
| Millboro | city | South Dakota | United States | 43.07 | -99.97 | 2509 | |
| Millbrook Colony | city | South Dakota | United States | 43.67 | -97.87 | 1243 | |
| Miller | city | South Dakota | United States | 44.52 | -98.99 | 1669 | |
| Miller Dale Colony | city | South Dakota | United States | 44.40 | -99.11 | 1873 | |
| Milltown | city | South Dakota | United States | 43.42 | -97.80 | 1223 | |
| Mina | city | South Dakota | United States | 45.43 | -98.76 | 1669 | |
| Minnekahta | city | South Dakota | United States | 43.43 | -103.69 | 4199 | |
| Miranda | city | South Dakota | United States | 44.97 | -98.96 | 1669 | |
| Miscol | city | South Dakota | United States | 45.68 | -101.16 | 2509 | |
| Mission | city | South Dakota | United States | 43.31 | -100.66 | 2585 | |
| Mission Hill | city | South Dakota | United States | 42.92 | -97.28 | 1184 | |
| Mission Ridge | city | South Dakota | United States | 44.69 | -100.80 | 1925 | |
| Mitchell | city | South Dakota | United States | 43.71 | -98.03 | 1669 | |
| Mobridge | city | South Dakota | United States | 45.54 | -100.43 | 1702 | |
| Moe | city | South Dakota | United States | 43.16 | -96.61 | 1669 | |
| Moenville | city | South Dakota | United States | 44.48 | -101.26 | 2509 | |
| Monroe | city | South Dakota | United States | 43.49 | -97.22 | 1669 | |
| Montrose | city | South Dakota | United States | 43.70 | -97.18 | 1669 | |
| Moon | city | South Dakota | United States | 43.95 | -104.01 | 6709 | |
| Moreau | city | South Dakota | United States | 45.36 | -100.40 | 1706 | |
| Morefield | city | South Dakota | United States | 43.69 | -96.77 | 1669 | |
| Moritz | city | South Dakota | United States | 44.83 | -96.56 | 1669 | |
| Morningside | city | South Dakota | United States | 44.37 | -98.19 | 1669 | |
| Morristown | city | South Dakota | United States | 45.94 | -101.72 | 2509 | |
| Mosher | city | South Dakota | United States | 43.47 | -100.30 | 2053 | |
| Mound City | city | South Dakota | United States | 45.73 | -100.07 | 1728 | |
| Mount Vernon | city | South Dakota | United States | 43.71 | -98.26 | 1669 | |
| Mud Butte | city | South Dakota | United States | 45.00 | -102.88 | 2900 | |
| Murdo | city | South Dakota | United States | 43.89 | -100.71 | 2509 | |
| Murphy | city | South Dakota | United States | 44.04 | -103.13 | 3349 | |
| Myersville | city | South Dakota | United States | 44.10 | -103.74 | 5944 | |
| Mystic | city | South Dakota | United States | 44.08 | -103.64 | 5282 |