| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Eagle Center | city | Iowa | United States | 42.34 | -92.36 | 964 | |
| Eagle City | city | Iowa | United States | 42.47 | -93.15 | 1049 | |
| Eagle Grove | city | Iowa | United States | 42.66 | -93.90 | 1118 | |
| Eagle Point | city | Iowa | United States | 42.53 | -90.64 | 830 | |
| Eagle Ridge Community | city | Iowa | United States | 42.04 | -91.55 | 830 | |
| Earlham | city | Iowa | United States | 41.49 | -94.12 | 1099 | |
| Earling | city | Iowa | United States | 41.78 | -95.42 | 1669 | |
| Earlville | city | Iowa | United States | 42.48 | -91.27 | 1010 | |
| Early | city | Iowa | United States | 42.46 | -95.15 | 1669 | |
| Easley | city | Iowa | United States | 42.31 | -94.40 | 1151 | |
| East Amana | city | Iowa | United States | 41.81 | -91.85 | 830 | |
| East Canton | city | Iowa | United States | 42.16 | -90.90 | 830 | |
| East Creston | city | Iowa | United States | 41.06 | -94.34 | 1669 | |
| East Des Moines | city | Iowa | United States | 41.57 | -93.55 | 830 | |
| East Iron Hills | city | Iowa | United States | 42.14 | -90.74 | 830 | |
| East Monticello | city | Iowa | United States | 42.25 | -91.17 | 830 | |
| East Ottumwa | city | Iowa | United States | 41.01 | -92.38 | 830 | |
| East Peru | city | Iowa | United States | 41.23 | -93.93 | 967 | |
| East Pleasant Plain | city | Iowa | United States | 41.14 | -91.85 | 830 | |
| East Port (historical) | city | Iowa | United States | 40.68 | -95.84 | 918 | |
| East Rapids | city | Iowa | United States | 41.96 | -91.64 | 830 | |
| East Rickardsville | city | Iowa | United States | 42.57 | -90.86 | 889 | |
| Eastgate Estate Park | city | Iowa | United States | 42.49 | -92.31 | 839 | |
| Easton Place | city | Iowa | United States | 41.61 | -93.57 | 830 | |
| Ebys Mill | city | Iowa | United States | 42.20 | -91.06 | 830 | |
| Echo | city | Iowa | United States | 41.74 | -95.94 | 1233 | |
| Echo Valley Mobile Home Park | city | Iowa | United States | 40.84 | -91.22 | 830 | |
| Eckards | city | Iowa | United States | 42.86 | -91.10 | 830 | |
| Eddyville | city | Iowa | United States | 41.16 | -92.64 | 830 | |
| Eden | city | Iowa | United States | 42.11 | -91.97 | 846 | |
| Edenville | city | Iowa | United States | 41.93 | -93.18 | 1010 | |
| Edgewood | city | Iowa | United States | 42.64 | -91.40 | 1177 | |
| Edinburg | city | Iowa | United States | 42.13 | -91.13 | 1010 | |
| Edmore | city | Iowa | United States | 42.56 | -90.68 | 830 | |
| Edna | city | Iowa | United States | 43.38 | -96.09 | 1669 | |
| Edwards (historical) | city | Iowa | United States | 42.57 | -92.26 | 915 | |
| Egan | city | Iowa | United States | 43.16 | -91.29 | 1122 | |
| Egralharve | city | Iowa | United States | 43.40 | -95.17 | 1669 | |
| Ehler | city | Iowa | United States | 42.31 | -91.51 | 967 | |
| Eifield (historical) | city | Iowa | United States | 41.41 | -93.03 | 830 | |
| Elberon | city | Iowa | United States | 42.01 | -92.32 | 905 | |
| Eldergrove | city | Iowa | United States | 43.24 | -91.22 | 1099 | |
| Eldon | city | Iowa | United States | 40.92 | -92.22 | 830 | |
| Eldora | city | Iowa | United States | 42.36 | -93.10 | 1099 | |
| Eldorado | city | Iowa | United States | 43.05 | -91.84 | 898 | |
| Eldridge | city | Iowa | United States | 41.66 | -90.58 | 830 | |
| Eleanor | city | Iowa | United States | 42.61 | -92.85 | 984 | |
| Elgin | city | Iowa | United States | 42.96 | -91.63 | 830 | |
| Elk Horn | city | Iowa | United States | 41.59 | -95.06 | 1669 | |
| Elk River Junction | city | Iowa | United States | 41.98 | -90.17 | 830 | |
| Elk Run Heights | city | Iowa | United States | 42.47 | -92.26 | 849 | |
| Elkader | city | Iowa | United States | 42.85 | -91.41 | 830 | |
| Elkhart | city | Iowa | United States | 41.79 | -93.52 | 971 | |
| Elkport | city | Iowa | United States | 42.74 | -91.28 | 830 | |
| Elkton | city | Iowa | United States | 42.80 | -95.37 | 1669 | |
| Elliott | city | Iowa | United States | 41.15 | -95.16 | 1092 | |
| Ellmaker | city | Iowa | United States | 40.97 | -92.08 | 830 | |
| Ellston | city | Iowa | United States | 40.84 | -94.11 | 1669 | |
| Ellsworth | city | Iowa | United States | 42.31 | -93.58 | 1125 | |
| Elm Spring | city | Iowa | United States | 43.31 | -96.49 | 1669 | |
| Elma | city | Iowa | United States | 43.25 | -92.44 | 1243 | |
| Elmira | city | Iowa | United States | 41.72 | -91.42 | 830 | |
| Elon | city | Iowa | United States | 43.26 | -91.32 | 1240 | |
| Elrick Junction | city | Iowa | United States | 41.10 | -91.12 | 830 | |
| Elvira | city | Iowa | United States | 41.86 | -90.36 | 830 | |
| Elwood | city | Iowa | United States | 41.99 | -90.74 | 830 | |
| Ely | city | Iowa | United States | 41.87 | -91.59 | 830 | |
| Emeline | city | Iowa | United States | 42.16 | -90.83 | 954 | |
| Emerson | city | Iowa | United States | 41.02 | -95.40 | 1059 | |
| Emery | city | Iowa | United States | 43.13 | -93.28 | 1194 | |
| Emmetsburg | city | Iowa | United States | 43.11 | -94.68 | 1223 | |
| Enterprise | city | Iowa | United States | 41.73 | -93.53 | 1000 | |
| Epworth | city | Iowa | United States | 42.45 | -90.93 | 1003 | |
| Erdmann Trailer Court | city | Iowa | United States | 42.79 | -96.17 | 1249 | |
| Ericson | city | Iowa | United States | 42.03 | -93.80 | 1102 | |
| Essex | city | Iowa | United States | 40.83 | -95.31 | 997 | |
| Estates West | city | Iowa | United States | 42.41 | -96.36 | 1095 | |
| Estherville | city | Iowa | United States | 43.40 | -94.83 | 1669 | |
| Euclid | city | Iowa | United States | 41.54 | -95.86 | 1046 | |
| Eureka | city | Iowa | United States | 40.77 | -95.84 | 928 | |
| Eureka (historical) | city | Iowa | United States | 41.22 | -91.71 | 830 | |
| Evander | city | Iowa | United States | 43.18 | -95.76 | 1669 | |
| Evans | city | Iowa | United States | 41.30 | -92.73 | 830 | |
| Evansdale | city | Iowa | United States | 42.47 | -92.28 | 830 | |
| Evanston | city | Iowa | United States | 42.43 | -94.06 | 1108 | |
| Eveland | city | Iowa | United States | 41.17 | -92.80 | 849 | |
| Evergreen Village | city | Iowa | United States | 42.56 | -96.34 | 1112 | |
| Everly | city | Iowa | United States | 43.16 | -95.33 | 1669 | |
| Ewart | city | Iowa | United States | 41.64 | -92.61 | 984 | |
| Exeelsior | city | Iowa | United States | 41.26 | -92.51 | 866 | |
| Exira | city | Iowa | United States | 41.59 | -94.88 | 1249 | |
| Exline | city | Iowa | United States | 40.65 | -92.84 | 1013 |