| Name | What | Region | Country | Lat | Long | Elev ft. | Pop est |
|---|---|---|---|---|---|---|---|
| Saguyaq | city | Alaska | United States | 58.84 | -158.55 | 98 | |
| Sagwon | city | Alaska | United States | 69.37 | -148.70 | 830 | |
| Saint George | city | Alaska | United States | 56.60 | -169.54 | 242 | |
| Saint John Harbor | city | Alaska | United States | 56.44 | -132.96 | 0 | |
| Saint Marys | city | Alaska | United States | 62.05 | -163.17 | 3 | |
| Saint Michael | city | Alaska | United States | 63.48 | -162.04 | 0 | |
| Saint Paul | city | Alaska | United States | 57.12 | -170.28 | 32 | |
| Saint Paul Harbor | city | Alaska | United States | 57.79 | -152.41 | 52 | |
| Saint Terese | city | Alaska | United States | 58.47 | -134.78 | 298 | |
| Salamatof | city | Alaska | United States | 60.62 | -151.32 | 127 | |
| Salmon Village | city | Alaska | United States | 66.57 | -142.60 | 830 | |
| Salt Chuck | city | Alaska | United States | 55.63 | -132.55 | 82 | |
| Sanak | city | Alaska | United States | 54.48 | -162.82 | 65 | |
| Sand Point | city | Alaska | United States | 55.34 | -160.50 | 68 | |
| Sannak | city | Alaska | United States | 54.48 | -162.82 | 65 | |
| Savonoski | city | Alaska | United States | 58.72 | -156.86 | 29 | |
| Savonoski (historical) | city | Alaska | United States | 58.53 | -155.32 | 36 | |
| Savoonga | city | Alaska | United States | 63.69 | -170.48 | 108 | |
| Saxman | city | Alaska | United States | 55.32 | -131.60 | 0 | |
| Scammon Bay | city | Alaska | United States | 61.84 | -165.58 | 830 | |
| Scow Bay | city | Alaska | United States | 56.77 | -132.96 | 311 | |
| Sedanka (historical) | city | Alaska | United States | 53.48 | -167.29 | 147 | |
| Selawik | city | Alaska | United States | 66.60 | -160.01 | 3 | |
| Seldovia | city | Alaska | United States | 59.44 | -151.71 | 137 | |
| Seldovia Village | city | Alaska | United States | 59.48 | -151.65 | 203 | |
| Seredka (historical) | city | Alaska | United States | 54.17 | -165.48 | 0 | |
| Serpentine Hot Springs | city | Alaska | United States | 65.86 | -164.71 | 830 | |
| Seversens | city | Alaska | United States | 59.75 | -154.82 | 45 | |
| Seward | city | Alaska | United States | 60.10 | -149.44 | 52 | |
| Shageluk | city | Alaska | United States | 62.68 | -159.56 | 62 | |
| Shaguiak | city | Alaska | United States | 58.84 | -158.55 | 98 | |
| Shaktoolik | city | Alaska | United States | 64.33 | -161.15 | 6 | |
| Sheldon Point | city | Alaska | United States | 62.53 | -164.84 | 0 | |
| Shelton (historical) | city | Alaska | United States | 65.23 | -164.82 | 42 | |
| Sheshalik | city | Alaska | United States | 66.99 | -162.83 | 0 | |
| Shevenak (historical) | city | Alaska | United States | 60.20 | -162.25 | 3 | |
| Shiniak (historical) | city | Alaska | United States | 59.80 | -161.95 | 3 | |
| Shinnapago (historical) | city | Alaska | United States | 65.17 | -166.12 | 830 | |
| Shirleyville | city | Alaska | United States | 61.01 | -151.41 | 0 | |
| Shishmaref | city | Alaska | United States | 66.26 | -166.07 | 3 | |
| Shlakaq' (historical) | city | Alaska | United States | 60.48 | -151.13 | 111 | |
| Shoreline Drive | city | Alaska | United States | 55.38 | -131.72 | 0 | |
| Shungnak | city | Alaska | United States | 66.89 | -157.14 | 98 | |
| Sidaru (historical) | city | Alaska | United States | 70.75 | -159.75 | 16 | |
| Siilvik | city | Alaska | United States | 66.60 | -160.01 | 3 | |
| Sikanasankian (historical) | city | Alaska | United States | 58.22 | -134.18 | 49 | |
| Siksatok (historical) | city | Alaska | United States | 52.43 | 173.60 | 830 | |
| Silver Bay (historical) | city | Alaska | United States | 56.98 | -135.12 | 830 | |
| Silvertip | city | Alaska | United States | 60.75 | -149.37 | 830 | |
| Simels (historical) | city | Alaska | United States | 63.59 | -157.21 | 111 | |
| Sisaguk (historical) | city | Alaska | United States | 54.65 | -163.30 | 0 | |
| Sitka | city | Alaska | United States | 57.05 | -135.33 | 0 | |
| Sitka City and Borough | city | Alaska | United States | 57.05 | -135.33 | 0 | |
| Sitkoh (historical) | city | Alaska | United States | 57.47 | -134.87 | 0 | |
| Sitnazuak (historical) | city | Alaska | United States | 64.55 | -165.70 | 45 | |
| Situk | city | Alaska | United States | 59.44 | -139.55 | 0 | |
| Situk Village (historical) | city | Alaska | United States | 59.45 | -139.57 | 3 | |
| Sivard | city | Alaska | United States | 60.10 | -149.44 | 52 | |
| Sivuqaq | city | Alaska | United States | 63.78 | -171.74 | 26 | |
| Skaguay | city | Alaska | United States | 59.46 | -135.31 | 830 | |
| Skagway | city | Alaska | United States | 59.46 | -135.31 | 830 | |
| Skakvey | city | Alaska | United States | 59.46 | -135.31 | 830 | |
| Skilak (historical) | city | Alaska | United States | 60.03 | -150.20 | 4445 | |
| Skittok (historical) | city | Alaska | United States | 60.55 | -151.27 | 3 | |
| Skolai (historical) | city | Alaska | United States | 61.42 | -142.60 | 1669 | |
| Skwentna | city | Alaska | United States | 61.99 | -151.40 | 137 | |
| Slana | city | Alaska | United States | 62.71 | -143.96 | 2509 | |
| Slaterville | city | Alaska | United States | 64.85 | -147.72 | 830 | |
| Sleetmute | city | Alaska | United States | 61.70 | -157.17 | 187 | |
| Snug Harbor | city | Alaska | United States | 60.49 | -149.78 | 830 | |
| Soldotna | city | Alaska | United States | 60.49 | -151.06 | 85 | |
| Solomon | city | Alaska | United States | 64.56 | -164.44 | 9 | |
| Soo City (historical) | city | Alaska | United States | 66.72 | -151.48 | 830 | |
| Sooghmeghat | city | Alaska | United States | 63.35 | -169.41 | 32 | |
| Soonkakat (historical) | city | Alaska | United States | 64.92 | -154.67 | 167 | |
| Sourdough (historical) | city | Alaska | United States | 61.36 | -142.73 | 1669 | |
| South Fairbanks | city | Alaska | United States | 64.83 | -147.72 | 830 | |
| South Naknek | city | Alaska | United States | 58.72 | -157.00 | 98 | |
| Sparks (historical) | city | Alaska | United States | 59.03 | -159.15 | 22 | |
| Spenard | city | Alaska | United States | 61.19 | -149.91 | 95 | |
| Spooner (historical) | city | Alaska | United States | 65.38 | -164.22 | 101 | |
| Squaw Harbor | city | Alaska | United States | 55.24 | -160.55 | 0 | |
| Standard | city | Alaska | United States | 64.78 | -148.53 | 383 | |
| Star (historical) | city | Alaska | United States | 64.93 | -141.28 | 849 | |
| Starr Hill | city | Alaska | United States | 58.30 | -134.40 | 830 | |
| Stebbins | city | Alaska | United States | 63.52 | -162.29 | 36 | |
| Sterling | city | Alaska | United States | 60.54 | -150.76 | 183 | |
| Stevens Village | city | Alaska | United States | 66.01 | -149.09 | 301 | |
| Stony River | city | Alaska | United States | 61.78 | -156.59 | 219 | |
| Strelna | city | Alaska | United States | 61.51 | -144.07 | 1669 | |
| Stuyahok | city | Alaska | United States | 62.06 | -160.95 | 830 | |
| Sulatna Crossing | city | Alaska | United States | 64.19 | -155.46 | 344 | |
| Sullivan (historical) | city | Alaska | United States | 65.07 | -166.20 | 291 | |
| Sullivan Camp | city | Alaska | United States | 65.06 | -166.20 | 370 | |
| Sulzer (historical) | city | Alaska | United States | 55.29 | -132.62 | 98 | |
| Sumdum (historical) | city | Alaska | United States | 57.67 | -133.48 | 200 | |
| Summit | city | Alaska | United States | 63.33 | -149.12 | 2509 | |
| Summit | city | Alaska | United States | 64.58 | -165.36 | 830 | |
| Sunbeam | city | Alaska | United States | 61.20 | -149.90 | 91 | |
| Sunik (historical) | city | Alaska | United States | 52.43 | 173.60 | 830 | |
| Sunnyside | city | Alaska | United States | 57.98 | -136.25 | 0 | |
| Sunrise | city | Alaska | United States | 60.89 | -149.42 | 170 | |
| Sunshine | city | Alaska | United States | 62.17 | -150.07 | 347 | |
| Suntrana | city | Alaska | United States | 63.85 | -148.85 | 1669 | |
| Sunvalluk (historical) | city | Alaska | United States | 64.57 | -166.05 | 0 | |
| Susitna | city | Alaska | United States | 61.54 | -150.51 | 88 | |
| Sutton | city | Alaska | United States | 61.71 | -148.89 | 830 | |
| Suvarov | city | Alaska | United States | 58.73 | -157.01 | 0 | |
| Suwarof | city | Alaska | United States | 58.73 | -157.01 | 0 | |
| Suworof | city | Alaska | United States | 58.73 | -157.01 | 0 |